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C. Difficile (Colitis)


Question

Two years ago our 4-year-old son had a blockage in his bowel. Recently he was in the hospital for 8 days with much pain. They did an upper GI series, endoscopy, CT scan and blood work, which were all negative. He has also had C.Difficile and colitis treated with antibiotics but with no improvement.

  1. Why not a lower GI series?

2. What other tests should be performed?

Answer of our experts


I assume that the pain is cramping with the diarrhea. C. difficile can be hard to treat and certainly can come back. If it doesn't respond to flagyl, we usually treat another cycle. You can also try oral vancomycin, but it is very expensive. We have often used Amphogel to bind the toxin (1/2cc/kg/dose 4 times a daynot by other meds as it will bind them) and either homemade yogurt or lactobacillus capsules to try and alter the flora enough to control the diarrhea and cramps. The prep we use is called Culturelle.

You don't usually want to do a barium enema if there is inflammation of the colon; they should have been able to lookfairly well with the CT scan.

CP/TK 7-13-10

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Recommendation(s)

Pain and Behaviour

R18
As pain can easily remain unrecognised in a child with CdLS, all care providers should be aware of the different manifestations and the possible sources of pain. Specific tools to assess pain are recommended.

Recommendation(s)

Gastrointestinal Problems

R28
Every new born suspected or proven to have CdLS should be carefully evaluated for signs and symptoms consistent with gastrointestinal malformations.

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