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CdLS – Syndrome, Disease or Disorder?


Question

J'ai différement entendu parler du SCdL comme d'une maladie, d'un trouble et d'un syndrome. Qu'est-ce qui fait que le SCdLest un syndrome, et non une maladie ou un trouble ?

Answer of our experts

The word syndrome has its roots in the Greek words “syn” (which means “together”) and “drom” (which means “running”). Literally it is the occurrence together of a sum of signs or symptoms. Syndrome usually connotes an abnormal state, but it may not be completely abnormal.

In contrast, both “disease” and “disorder” generally refer to a single abnormality or the single abnormal function of any body part, organ or system, which is manifested by the characteristic set of symptoms and signs. Syndromes may have single causes but are generally recognized by their multiple manifestations. Diseases are usually diagnosed by their single cause.

Take the lung, for example. Pneumonia is a disease or disorder which, specifically, an inflammation of lung tissue. It may be caused by any number of bacteria or other kinds of infectious organisms, but it is always a lung tissue inflammation. On the other hand, the Pickwickian Syndrome is a syndrome of breathing insufficiency associated with being fat, like Mr. Pickwick. The breathing problem occurs when there is not enough movement of the diaphragm, and is accompanied by other signs of breathing trouble i.e. blue tint to the skin, etc. Syndromes are diagnosed by adding up all the signs.

LJ/TK 7-13-10

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